Катедра по фармакология, токсикология и фармакотерапия / Department of Pharmacology, Toxicology and Pharmacotherapy
Recent Submissions
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Neuropharmacological Investigation of Myrtenal Conjugates with Aminoadamantane // Неврофармакологично изследване на миртеналови конюгати с аминоадамантан
(Medical University of Varna, 2024)Neurodegenerative diseases are characterised by multifactorial pathoetiology. The search for potential pharmacological agents with a complex mechanism of action involves various substances, most of which are natural ... -
Synthesis of Peptide Molecules, Analogues of Lactoferricin and in Vitro Screening for Antimicrobial and Antitumor Activity // Синтезиране на пептидни молекули, аналози на лактоферицин, и изследване за антимикробно и противотуморно действие
(Medical University of Varna, 2023)Antibiotic resistance and the increasing number of diagnosed oncological diseases affect all areas of healthcare, drain the economy, and impact society. The leading importance of developing resistant bacterial strains is ... -
Isolation and Analysis of Methylxanthine Fraction, Catechin Fraction and Total Bancha Green Tea Extract and Study of Their Influence on the Pharmacokinetics of Sildenafil in Rats // Изолиране и анализ на метилксантинова фракция, катехинова фракция и цялостен екстракт от зелен чай Банча и проучване на влиянието им върху фармакокинетиката на силденафил при плъхове
(Medical University of Varna, 2022)Green tea is known for a number of beneficial effects such as antioxidant, anti-inflammatory and antimicrobial activity, antitumor effect and others. Tea leaves contain a wide variety of biologically active substances ... -
Characteristics of Acute Medicinal Poisoning in Varna District over a 30-Year Period // Характеристика на острите медикаментозни отравяния във Варненска област за 30-годишен период
(Medical University of Varna, 2021)Poisoning is a significant public health problem. According to WHO data, in 2016, more than 1,206,000 people died due to accidental poisoning. There are significant differences in patterns of poisoning between different ... -
Pharmacological Studies of Steroid Hormones, Natural Products and Newly Synthesized 2h-Substituted Hydrasid-Hydrasones in Experimental Models of Epilepsy, Pain and Osteoporosis // Фармакологични проучвания на стероидни хормони, природни продукти и новосинтезирани 2H-субституирани хидразид-хидразони в експериментални модели на епилепсия, болка и остеопороза
(Medical University of Varna, 2020)Epilepsy is one of the most severe neurological conditions. Based on a number of clinical and laboratory studies it is known that steroid hormones have a significant role in epileptogenesis. One of the purposes of this ... -
Some Deontological Considerations Related to Features of Communication with Patients with Acute Intoxication // Някои деонтологични проблеми, свързани с особеностите на комуникацията с пациенти с остри отравяния
(Medical University of Varna, 2021)Deontological problems are common in clinical toxicology. This is a current socially-significant topic because of the large number of acute poisonings. The aim of the dissertation is to examine the deontological considerations ... -
Study of the Effects of Intravenous Lipid Infusion in Acute Intoxications with Some Xenobiotics // Проучване ефектите на интравенозна липидна инфузия при остри интоксикации с някои ксенобиотици
(Medical University of Varna, 2021)We investigate the protective role of intravenous infusion of fat emulsions as an antidote in acute intoxications with some lipophilic xenobiotics, exhibiting neurotoxic effects - drugs and organophosphorus pesticides ... -
New aspects in the liquid chromatographic analysis of Capecitabine in samples of biological and non-biological origin // Нови аспекти в течнохроматографския анализ на Capecitabine в проби от биологичен и небиологичен произход
(Medical University of Varna, 2021)The treatment of malignancies is a serious challenge for the modern healthcare system. Evidence of this is the drastic increase in morbidity and mortality due to cancer globally (by 44% and 26%, respectively). On the other ... -
European Practices and Standards for Digital Forms of Continuing Education of Medical Professionals in The Field of Medicines Policy // Европейски практики и стандарти за дигитални форми на продължаващо обучение на медицински специалисти в сферата на лекарствената политика
(Medical University of Varna, 2021)Continuing education as a key element of lifelong learning becomes increasingly important in the modern globalized world as access to information is facilitated, and constantly upgraded digital methods of education strengthen ... -
Identification, Analysis and Evaluation of Pharmacokinetic and Pharmacodynamics Drug Interaction // Идентификация, анализ и оценка на фармакокинетични и фармакодинамични лекарствени взаимодействия
(Medical University of Varna, 2020)Идентификацията, анализът и оценката на лекарствени взаимодействия е от изключително важно значение в предклиничния етап при разработката и внедряването на нови лекарства. Всички нови лекарствени молекули, субстрати, ... -
Cardioprotective Effect of Lipid Emulsion on Acute Exogenous Drug Intoxications // Кардиопротективен ефект на липидна емулсия при остри екзогенни интоксикации с медикаменти
(Medical University of Varna, 2020)Acute drug intoxication is a major problem worldwide, with antidepressants, neuroleptics, and cardiovascular drugs being the most commonly overdosed drugs. Most of these do not have a specific antidote and cause serious ... -
Pharmacotherapeutic Study, Potential Side and Toxic Effects of Cardioactive Drugs in the Treatment of Hospitalized Patients with Chronic Heart Failure /// Фармакотерапевтично проучване, потенциални странични и токсични ефекти на кардиоактивни медикаменти при лечение на хоспитализирани пациенти с хронична сърдечна недостатъчност
(Medical University of Varna, 2018)Систематизирани и обобщени са демографските данни и медикаментозното лечение на 535 хоспитализирани пациенти с диагноза хронична обострена сърдечна недостатъчност, със запазена (СНзФИ) и редуцирана фракция на изтласкване ...
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